Vitamin & derivatives
0102030405
Sulbutiamine/ Bisibutiamine/ Vitamin B1 derivative/ Synthetic derivative of thiamine
C32H46N8O6S2
Description
Sulbutiamine (CAS No. 3286-46-2) is a highly fat-soluble derivative of vitamin B1 (thiamine). It forms a unique structure through sulfonic acid group modification, significantly improving bioavailability and neural targeting. Its nutritional and health value far exceeds that of ordinary vitamin B1.
Technical Advantage Analysis
Enhanced nerve penetration: The fat-soluble structure increases its blood-brain barrier penetration by 3 times, and the concentration in the brain is 2.5 times that of ordinary B1, directly supporting neuronal metabolism and myelin repair.
Sustained release and long-acting mechanism: As a prodrug, it slowly releases active thiamine in the body, and the action time is extended to 12 hours, continuously supporting energy metabolism.
Multi-target synergy: Synchronously improve mitochondrial ATP synthesis, acetylcholine transmission and GABA inhibitory neurotransmitter balance, forming a closed loop of neuroprotection-cognitive enhancement.
Core role of nutritional health
1.Cognitive empowerment
Memory enhancement: Promote acetylcholine synthesis in the hippocampus and improve information processing ability.
Focus improvement: Optimize the energy supply of the prefrontal cortex and prolong the efficient working state.
Physical fitness optimization
Anti-fatigue: accelerates muscle cell glycolysis, improves exercise endurance and recovery speed.
Cardiovascular support: maintains myocardial cell ATP levels, stabilizes heart rate and blood pressure.
2.Emotional management
Anxiety relief: regulates GABA receptor activity and balances central nervous system excitability.
Stress coping: inhibits excessive cortisol secretion and protects the hippocampus from oxidative damage.
3. Nerve repair
Peripheral nerve support: improves numbness and tingling caused by diabetic neuropathy.
Brain health maintenance: removes free radicals and delays neuronal aging.
4.Application scenario expansion
It is widely used in anti-fatigue dietary supplements, sports nutrition formulas and brain health products. Clinical studies have shown that it has an auxiliary improvement effect on neurasthenia and postherpetic neuralgia. Its high fat solubility makes it suitable for the development of oral preparations and functional beverages, making it a preferred solution for upgrading and replacing vitamin B1.