Riboflavin Sodium Phosphate - Vitamin B2 R5P Suppliers from China | Quality Factory Products
C17H24N4NaO11P
Riboflavin Sodium Phosphate (R5P) is an active phosphate derivative of vitamin B2 (riboflavin). It significantly improves water solubility and bioavailability through modification of phosphate groups. Its technical advantages and nutritional and health value far exceed ordinary riboflavin.
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💧Absorption & Utilization Rate Increased The solubility of riboflavin sodium phosphate in water reaches 50 mg/mL, which is dozens of times that of ordinary riboflavin. It can be made into multiple dosage forms such as injection and eye drops, breaking through the limitation that riboflavin can only be absorbed orally, and the clinical application scenarios are significantly expanded.
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⚡Enhanced Metabolic Activity As a precursor of coenzymes FAD and FMN, it directly participates in the energy metabolism of the cell respiratory chain, promotes the conversion efficiency of sugar, fat and protein, and its biological activity is about 40% higher than that of riboflavin.
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🛡️Stability Upgrade It is thermally stable under acidic to neutral conditions, and its light-resistant decomposition ability is enhanced, which is convenient for processing, storage and multi-scenario application.
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Energy Metabolism Engine
Activate mitochondrial oxidative phosphorylation reaction, improve ATP synthesis efficiency, and improve exercise endurance and fatigue recovery.
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Antioxidant Defense System
Remove free radicals, inhibit lipid peroxidation, protect cell membrane integrity, delay aging and chronic disease risks.
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Mucosal Health Protection
Repair oral and gastrointestinal mucosa, prevent angular cheilitis, cheilitis, glossitis, and relieve mucosal damage after radiotherapy and chemotherapy.
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Visual Function Support
Maintain retinal photoreceptor cell metabolism, reduce blue light damage, improve night vision and visual fatigue.
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Blood System Strengthening
Promote iron absorption and utilization, increase hemoglobin synthesis, and assist in improving iron deficiency anemia.
It is used in the medical field for the treatment of vitamin B2 deficiency, as a nutritional enhancer in the food industry (dairy products, grains), improves skin barrier function in the cosmetics field, and improves the growth performance of livestock and poultry by adding feed. Its multi-target mechanism of action (metabolic regulation + antioxidant + tissue repair) provides an integrated solution for health intervention and becomes the preferred choice for upgrading and replacing vitamin B2.
Q1 What is Riboflavin Sodium Phosphate (R5P) and how does it differ from regular riboflavin?
Riboflavin Sodium Phosphate (R5P) is an active phosphate derivative of vitamin B2 (riboflavin). Unlike regular riboflavin, R5P has dramatically improved water solubility (up to 50 mg/mL), greater bioavailability, and approximately 40% higher biological activity, making it far more effective for clinical and nutritional applications.
Q2 What are the main clinical applications of Riboflavin Sodium Phosphate?
R5P is widely used in the medical field to treat vitamin B2 deficiency. Thanks to its high water solubility, it can be formulated into injections and eye drops, enabling clinical scenarios beyond oral administration. It is also applied in post-radiotherapy and post-chemotherapy mucosal recovery.
Q3 How does Riboflavin Sodium Phosphate support energy metabolism?
R5P acts as a direct precursor to coenzymes FAD and FMN, which are essential components of the cell respiratory chain. It activates mitochondrial oxidative phosphorylation, enhances ATP synthesis efficiency, and promotes the conversion of sugars, fats, and proteins into usable energy — improving endurance and speeding up fatigue recovery.
Q4 Is Riboflavin Sodium Phosphate stable during storage and processing?
Yes. Riboflavin Sodium Phosphate demonstrates strong thermal stability under acidic to neutral conditions, and it has improved resistance to light-induced decomposition compared to ordinary riboflavin. These properties make it highly suitable for industrial processing, long-term storage, and use across multiple application environments.
Q5 In which industries is Riboflavin Sodium Phosphate commonly used?
R5P has a broad range of industry applications: it serves as a nutritional enhancer in food products (dairy and grain-based items), improves skin barrier function in cosmetics formulations, treats B2 deficiency in the medical sector, and enhances livestock and poultry growth performance as a feed additive.
Q6 Can Riboflavin Sodium Phosphate help with eye health and vision?
Yes. R5P supports visual function by maintaining the metabolic activity of retinal photoreceptor cells. It helps reduce damage caused by blue light exposure, improves night vision capability, and alleviates symptoms of visual fatigue — making it a valuable ingredient in both eye care supplements and ophthalmic formulations.



