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Riboflavin-5'-Phosphate Suppliers in China | Quality Vitamin B2 R5P from Reliable Factory
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Riboflavin-5'-Phosphate Suppliers in China | Quality Vitamin B2 R5P from Reliable Factory

Riboflavin 5'-phosphate is a vibrant yellow to orange crystalline powder known for its excellent solubility in water and minimal solubility in ethanol. As one of the leading suppliers from China, our factory ensures the highest quality standards for this essential nutrient. Ideal for various applications in the pharmaceutical and food industries, Riboflavin 5'-phosphate plays a crucial role in energy metabolism and cellular function. Choose our reliable China-based factory for your Riboflavin 5'-phosphate needs and experience unparalleled quality and service
  • CAS: 6184-17-4

C17H24N4NaO11P
Riboflavin Sodium Phosphate Structure
Description
Riboflavin Sodium Phosphate (R5P) is an active phosphate derivative of vitamin B2 (riboflavin). It significantly improves water solubility and bioavailability through modification of phosphate groups. Its technical advantages and nutritional and health value far exceed ordinary riboflavin.
Comparison of Technical Advantages
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Absorption & Utilization Rate Increased
The solubility of riboflavin sodium phosphate in water reaches 50 mg/mL, which is dozens of times that of ordinary riboflavin. It can be made into multiple dosage forms such as injection and eye drops, breaking through the limitation that riboflavin can only be absorbed orally, and the clinical application scenarios are significantly expanded.
Enhanced Metabolic Activity
As a precursor of coenzymes FAD and FMN, it directly participates in the energy metabolism of the cell respiratory chain, promotes the conversion efficiency of sugar, fat and protein, and its biological activity is about 40% higher than that of riboflavin.
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Stability Upgrade
It is thermally stable under acidic to neutral conditions, and its light-resistant decomposition ability is enhanced, which is convenient for processing, storage and multi-scenario application.
In-Depth Analysis of Nutrition & Health
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Energy Metabolism Engine
Activates mitochondrial oxidative phosphorylation reaction, improves ATP synthesis efficiency, and enhances exercise endurance and fatigue recovery.
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Antioxidant Defense System
Removes free radicals, inhibits lipid peroxidation, protects cell membrane integrity, and delays aging and chronic disease risks.
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Mucosal Health Protection
Repairs oral and gastrointestinal mucosa, prevents angular cheilitis, cheilitis, glossitis, and relieves mucosal damage after radiotherapy and chemotherapy.
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Visual Function Support
Maintains retinal photoreceptor cell metabolism, reduces blue light damage, and improves night vision and visual fatigue.
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Blood System Strengthening
Promotes iron absorption and utilization, increases hemoglobin synthesis, and assists in improving iron deficiency anemia.
Clinical & Health Care Applications
It is used in the medical field for the treatment of vitamin B2 deficiency, as a nutritional enhancer in the food industry (dairy products, grains), improves skin barrier function in the cosmetics field, and improves the growth performance of livestock and poultry by adding feed. Its multi-target mechanism of action (metabolic regulation + antioxidant + tissue repair) provides an integrated solution for health intervention and becomes the preferred choice for upgrading and replacing vitamin B2.
🏥 Medical Treatment 🥛 Food Industry 💄 Cosmetics 🐄 Animal Feed ⚗️ Nutritional Enhancement
Frequently Asked Questions (FAQ)
Q What is Riboflavin Sodium Phosphate (R5P) and how does it differ from regular riboflavin?
Riboflavin Sodium Phosphate (R5P) is a phosphate-modified, water-soluble derivative of vitamin B2 (riboflavin). Unlike regular riboflavin, it has dramatically higher water solubility (up to 50 mg/mL), enhanced bioavailability, greater biological activity (~40% higher), and improved stability, allowing it to be used in injectable and topical dosage forms in addition to oral administration.
Q Why is the water solubility of Riboflavin Sodium Phosphate important?
High water solubility enables Riboflavin Sodium Phosphate to be formulated into a wider range of delivery forms — including injections, eye drops, and topical solutions — making it suitable for patients who cannot absorb nutrients orally. It also ensures more consistent dosing and improved absorption efficiency in clinical settings.
Q What are the main health benefits of Riboflavin Sodium Phosphate?
Key health benefits include boosting cellular energy metabolism (ATP production), providing antioxidant defense against free radicals, protecting mucosal tissues in the mouth and digestive tract, supporting retinal health and visual function, and enhancing iron absorption to help prevent iron deficiency anemia.
Q In which industries is Riboflavin Sodium Phosphate commonly applied?
Riboflavin Sodium Phosphate is widely used across multiple industries: in medicine for treating vitamin B2 deficiency; in the food industry as a nutritional enhancer in dairy products and grains; in cosmetics to improve skin barrier function; and in animal feed to support livestock and poultry growth performance.
Q How does Riboflavin Sodium Phosphate support energy metabolism at the cellular level?
As a direct precursor to the coenzymes FAD (flavin adenine dinucleotide) and FMN (flavin mononucleotide), Riboflavin Sodium Phosphate plays a central role in the mitochondrial respiratory chain. It activates oxidative phosphorylation, improves the efficiency of ATP synthesis, and accelerates the metabolic conversion of carbohydrates, fats, and proteins.
Q Is Riboflavin Sodium Phosphate stable during manufacturing and storage?
Yes. Riboflavin Sodium Phosphate demonstrates improved thermal stability under acidic to neutral conditions compared to standard riboflavin. Its enhanced resistance to light-induced decomposition makes it well-suited for industrial processing, long-term storage, and use across a variety of manufacturing environments without significant degradation.