Pyruvic Acid/ 2-Ketopropionic Acid/ ACETYLFORMIC ACID
C3H4O3
Description
CAS No.: 127-17-3 | Molecular formula: C₃H₄O₃ | Molecular weight: 88.06
Pyruvate is a key intermediate product in the metabolism of sugar, fat and protein. It participates in the tricarboxylic acid cycle (TCA cycle) and energy generation. In recent years, it has become a popular ingredient in the field of nutrition and health care due to its unique role in metabolic regulation, anti-oxidation and weight management. The following are its core nutrition and health functions and technical advantages:
Core nutrition and health functions
1.Energy metabolism and sports performance improvement
Pyruvate directly participates in the tricarboxylic acid cycle in mitochondria, promotes the conversion of glucose into adenosine triphosphate (ATP), and enhances cellular energy supply. Studies have shown that it can increase the activity of lactate dehydrogenase (LDH) and creatine kinase (CK), accelerate the removal of lactate after exercise, relieve muscle fatigue and prolong endurance.
2.Weight management and fat metabolism
Pyruvate promotes fat oxidation and inhibits fat synthesis by activating the pyruvate dehydrogenase complex (PDH). Clinical trials have shown that daily supplementation of calcium pyruvate (6-10 g) can increase basal metabolic rate, reduce visceral fat accumulation, and assist in weight management.
3.Antioxidant and skin health
As a natural antioxidant, pyruvate's ability to scavenge free radicals can reduce the damage of oxidative stress to skin collagen. Its derivatives (such as pyruvate-FITC) have shown in studies to inhibit the formation of advanced glycation end products (AGEs), delay skin aging and improve inflammatory symptoms such as acne.
4.Cardiovascular and blood sugar regulation
Pyruvate inhibits the formation of atherosclerotic plaques by reducing the risk of low-density lipoprotein (LDL) oxidation. At the same time, its ability to promote glucose metabolism can improve insulin sensitivity and help maintain blood sugar homeostasis.
5.Liver detoxification and metabolic support
As a metabolic intermediate, pyruvate participates in the conversion of amino acids and lipids, reducing the burden on the liver. Its heavy metal chelating properties (such as binding lead and cadmium) can accelerate the excretion of toxins and protect liver cell function.
Applicable groups and recommended solutions
Sports enthusiasts: enhance endurance and accelerate recovery after exercise;
Weight management group: promote fat metabolism and reduce visceral fat;
Metabolic syndrome patients: assist in regulating blood sugar and blood lipids;
Antioxidant demanders: delay skin aging and improve photodamage.



