O-Phospho-L-Threonine Suppliers in China | High-Quality Threoninium Dihydrogen Phosphate from Factory
C4H10NO6P
📋 Description
L-O-phospho-threonine (O-Phospho-L-threonine, CAS No. 1114-81-4) is a phosphorylated derivative of threonine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care.
⚙️ Technical Advantages Analysis
📡 Signal Transduction Enhancement
As a biological signal molecule, the phosphate group activates the protein kinase cascade reaction, regulates cell metabolism, differentiation and stress adaptation. Its negative charge characteristics enhance the affinity with the target protein and improve the efficiency of signal transduction.
⚡ Metabolic Regulation Upgrade
Promote glycogen synthase phosphorylation and accelerate glycogen storage; synchronously activate the pyruvate dehydrogenase complex and optimize the efficiency of mitochondrial ATP generation.
🛡️ Stability Improvement
Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
💊 Core Role of Nutrition and Health Care
🩹 1. Cell Repair and Regeneration
Wound Healing
Activate fibroblast proliferation, promote orderly deposition of collagen, and shorten the wound healing cycle.
Muscle Recovery
Reduce the level of creatine kinase after exercise and relieve delayed muscle soreness.
🦠 2. Immune Empowerment
Lymphocyte Activation
Enhance T/B cell receptor signal transduction, increase antibody secretion and diversity.
Anti-inflammatory Regulation
Inhibit NF-κB pathway, reduce pro-inflammatory factors TNF-α, IL-6 secretion.
Neuroprotection — Antioxidant Barrier
Upregulate glutathione peroxidase activity and scavenge free radicals.
Synaptic Plasticity
Promote brain-derived neurotrophic factor (BDNF) synthesis and maintain neuronal network stability.
🏋️ 3. Sports Nutrition Support
Energy Optimization
Improve muscle cell glycolysis efficiency and prolong exercise endurance.
Lactic Acid Metabolism
Accelerate lactate dehydrogenase reaction and shorten post-exercise recovery time.
🔬 4. Application Scenario Expansion
Widely used in sports nutrition supplements, postoperative recovery formulas and anti-aging health products. Clinical studies have shown that it has the potential to assist in improving metabolic syndrome and neurodegenerative diseases. Its phosphorylated structure makes it suitable for oral preparations and functional food development, becoming a targeted nutritional solution for threonine upgrade replacement.
❓ Frequently Asked Questions (FAQ)
Q
What is L-O-Phospho-Threonine (CAS No. 1114-81-4)?
L-O-Phospho-Threonine (O-Phospho-L-Threonine, CAS No. 1114-81-4) is a phosphorylated amino acid derivative of threonine. The introduction of a phosphate group significantly enhances its biological activity, water solubility, and functional diversity, making it valuable in nutrition, health care, and clinical research.
Q
How does L-O-Phospho-Threonine support the immune system?
It enhances T/B cell receptor signal transduction to boost antibody production, and inhibits the NF-κB inflammatory pathway to reduce pro-inflammatory cytokines such as TNF-α and IL-6, providing comprehensive immune support and anti-inflammatory regulation.
Q
What are the benefits of L-O-Phospho-Threonine for sports and exercise recovery?
It improves muscle cell glycolysis efficiency to extend exercise endurance, accelerates lactate dehydrogenase reactions to speed up post-exercise recovery, and helps reduce delayed muscle soreness by lowering post-exercise creatine kinase levels.
Q
What makes L-O-Phospho-Threonine different from regular threonine?
Unlike standard threonine, L-O-Phospho-Threonine features a phosphate group that enhances molecular polarity, water solubility, and thermal stability. This modification enables it to activate protein kinase cascades, regulate cell metabolism more effectively, and expand its use in advanced formulation development.
Q
In what types of products is L-O-Phospho-Threonine commonly used?
It is widely applied in sports nutrition supplements, postoperative recovery formulas, anti-aging health products, oral preparations, and functional foods. Its phosphorylated structure makes it an ideal targeted nutritional solution for replacing standard threonine in premium formulations.
Q
Does L-O-Phospho-Threonine have any neuroprotective effects?
Yes. It upregulates glutathione peroxidase activity to scavenge free radicals and provides an antioxidant barrier for neurons. Additionally, it promotes brain-derived neurotrophic factor (BDNF) synthesis and supports synaptic plasticity, helping to maintain neuronal network stability. Clinical research suggests potential in assisting the management of neurodegenerative diseases.




