Amino acids
0102030405
O-Phospho-L-threonine L-Phosphothreonine/ Threoninium Dihydrogen Phosphate/ O-Phosphothreonine
C4H10NO6P
Description
L-O-phospho-threonine (O-Phospho-L-threonine, CAS No. 1114-81-4) is a phosphorylated derivative of threonine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care.
Technical Advantages Analysis
Signal transduction enhancement: As a biological signal molecule, the phosphate group activates the protein kinase cascade reaction, regulates cell metabolism, differentiation and stress adaptation. Its negative charge characteristics enhance the affinity with the target protein and improve the efficiency of signal transduction.
Metabolic regulation upgrade: Promote glycogen synthase phosphorylation and accelerate glycogen storage; synchronously activate the pyruvate dehydrogenase complex and optimize the efficiency of mitochondrial ATP generation.
Stability improvement: Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
Core role of nutrition and health care
1.Cell repair and regeneration
Wound healing: Activate fibroblast proliferation, promote orderly deposition of collagen, and shorten the wound healing cycle.
Muscle recovery: Reduce the level of creatine kinase after exercise and relieve delayed muscle soreness.
2.Immune empowerment
Lymphocyte activation: Enhance T/B cell receptor signal transduction, increase antibody secretion and diversity.
Anti-inflammatory regulation: Inhibit NF-κB pathway, reduce pro-inflammatory factors TNF-α, IL-6 secretion.
Neuroprotection
Antioxidant barrier: Upregulate glutathione peroxidase activity and scavenge free radicals.
Synaptic plasticity: Promote brain-derived neurotrophic factor (BDNF) synthesis and maintain neuronal network stability.
3.Sports nutrition support
Energy optimization: Improve muscle cell glycolysis efficiency and prolong exercise endurance.
Lactic acid metabolism: Accelerate lactate dehydrogenase reaction and shorten post-exercise recovery time.
4.Application scenario expansion
Widely used in sports nutrition supplements, postoperative recovery formulas and anti-aging health products. Clinical studies have shown that it has the potential to assist in improving metabolic syndrome and neurodegenerative diseases. Its phosphorylated structure makes it suitable for oral preparations and functional food development, becoming a targeted nutritional solution for threonine upgrade replacement.