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O-Phospho-L-Threonine - High-Quality Threoninium Dihydrogen Phosphate from China Suppliers and Factory
C4H10NO6P
📋 Description
L-O-phospho-threonine (O-Phospho-L-threonine, CAS No. 1114-81-4) is a phosphorylated derivative of threonine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care.
⚙️ Technical Advantages Analysis
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🔬Signal Transduction Enhancement As a biological signal molecule, the phosphate group activates the protein kinase cascade reaction, regulates cell metabolism, differentiation and stress adaptation. Its negative charge characteristics enhance the affinity with the target protein and improve the efficiency of signal transduction.
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⚡Metabolic Regulation Upgrade Promote glycogen synthase phosphorylation and accelerate glycogen storage; synchronously activate the pyruvate dehydrogenase complex and optimize the efficiency of mitochondrial ATP generation.
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🛡️Stability Improvement Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
💊 Core Role of Nutrition and Health Care
🩹 1. Cell Repair & Regeneration
- Wound Healing: Activate fibroblast proliferation, promote orderly deposition of collagen, and shorten the wound healing cycle.
- Muscle Recovery: Reduce the level of creatine kinase after exercise and relieve delayed muscle soreness.
🦠 2. Immune Empowerment
- Lymphocyte Activation: Enhance T/B cell receptor signal transduction, increase antibody secretion and diversity.
- Anti-inflammatory Regulation: Inhibit NF-κB pathway, reduce pro-inflammatory factors TNF-α, IL-6 secretion.
- Neuroprotection: Upregulate glutathione peroxidase activity and scavenge free radicals.
- Synaptic Plasticity: Promote BDNF synthesis and maintain neuronal network stability.
🏋️ 3. Sports Nutrition Support
- Energy Optimization: Improve muscle cell glycolysis efficiency and prolong exercise endurance.
- Lactic Acid Metabolism: Accelerate lactate dehydrogenase reaction and shorten post-exercise recovery time.
🌿 4. Application Scenario Expansion
- Sports nutrition supplements
- Postoperative recovery formulas
- Anti-aging health products
- Oral preparations & functional food development
- Targeted nutritional solution for threonine upgrade replacement
📌 Clinical Potential
Clinical studies have shown that O-Phospho-L-threonine has the potential to assist in improving metabolic syndrome and neurodegenerative diseases. Its phosphorylated structure makes it suitable for oral preparations and functional food development, becoming a targeted nutritional solution for threonine upgrade replacement.
❓ Frequently Asked Questions
Q
What is O-Phospho-L-threonine (CAS 1114-81-4)?
O-Phospho-L-threonine is a phosphorylated derivative of the amino acid threonine, with the molecular formula C₄H₁₀NO₆P. The addition of a phosphate group significantly enhances its biological activity, making it valuable in nutrition, health care, and pharmaceutical applications.
Q
How does O-Phospho-L-threonine support immune function?
It enhances T/B cell receptor signal transduction to increase antibody secretion and diversity. Additionally, it inhibits the NF-κB inflammatory pathway, reducing pro-inflammatory cytokines such as TNF-α and IL-6, thereby supporting a balanced immune response.
Q
What are the sports nutrition benefits of O-Phospho-L-threonine?
It improves muscle cell glycolysis efficiency to prolong exercise endurance and accelerates lactate dehydrogenase reactions to shorten post-exercise recovery time. It also helps reduce creatine kinase levels after exercise, relieving delayed onset muscle soreness (DOMS).
Q
Why is phosphorylation important for the stability of this compound?
Phosphorylation modification enhances the molecular polarity of threonine, which improves its water solubility and thermal stability. This makes it easier to formulate into oral preparations, functional foods, and health supplements with a broader range of application scenarios.
Q
What metabolic functions does O-Phospho-L-threonine regulate?
It promotes glycogen synthase phosphorylation to accelerate glycogen storage, and synchronously activates the pyruvate dehydrogenase complex to optimize mitochondrial ATP generation efficiency, supporting overall cellular energy metabolism.
Q
In which types of products is O-Phospho-L-threonine commonly used?
It is widely used in sports nutrition supplements, postoperative recovery formulas, anti-aging health products, and functional food development. Clinical research also suggests potential applications in assisting the management of metabolic syndrome and neurodegenerative diseases.