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O-Phospho-L-threonine - High-Quality Threonine Suppliers and Factory in China
C4H10NO6P
Description
L-O-phospho-threonine (O-Phospho-L-threonine, CAS No. 1114-81-4) is a phosphorylated derivative of threonine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care.
Technical Advantages Analysis
⚡
Signal Transduction Enhancement
As a biological signal molecule, the phosphate group activates the protein kinase cascade reaction, regulates cell metabolism, differentiation and stress adaptation. Its negative charge characteristics enhance the affinity with the target protein and improve the efficiency of signal transduction.
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Metabolic Regulation Upgrade
Promote glycogen synthase phosphorylation and accelerate glycogen storage; synchronously activate the pyruvate dehydrogenase complex and optimize the efficiency of mitochondrial ATP generation.
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Stability Improvement
Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
Core Role of Nutrition and Health Care
1
Cell Repair & Regeneration
- Wound Healing: Activate fibroblast proliferation, promote orderly deposition of collagen, and shorten the wound healing cycle.
- Muscle Recovery: Reduce the level of creatine kinase after exercise and relieve delayed muscle soreness.
2
Immune Empowerment
- Lymphocyte Activation: Enhance T/B cell receptor signal transduction, increase antibody secretion and diversity.
- Anti-inflammatory Regulation: Inhibit NF-κB pathway, reduce pro-inflammatory factors TNF-α, IL-6 secretion.
- Neuroprotection / Antioxidant: Upregulate glutathione peroxidase activity and scavenge free radicals.
- Synaptic Plasticity: Promote BDNF synthesis and maintain neuronal network stability.
3
Sports Nutrition Support
- Energy Optimization: Improve muscle cell glycolysis efficiency and prolong exercise endurance.
- Lactic Acid Metabolism: Accelerate lactate dehydrogenase reaction and shorten post-exercise recovery time.
4
Application Scenario Expansion
- Sports nutrition supplements
- Postoperative recovery formulas
- Anti-aging health products
- Oral preparations & functional food development
🔬 Clinical Potential
Clinical studies have shown that it has the potential to assist in improving metabolic syndrome and neurodegenerative diseases. Its phosphorylated structure makes it suitable for oral preparations and functional food development, becoming a targeted nutritional solution for threonine upgrade replacement.
Frequently Asked Questions
Q
What is L-O-Phospho-Threonine (CAS No. 1114-81-4)?
A
L-O-Phospho-Threonine is a phosphorylated derivative of the amino acid threonine. The introduction of a phosphate group significantly enhances its biological activity and functional diversity, making it a valuable ingredient in nutrition and health care applications.
Q
How does L-O-Phospho-Threonine support immune function?
A
It enhances T/B cell receptor signal transduction to increase antibody secretion and diversity. Additionally, it inhibits the NF-κB pathway and reduces the secretion of pro-inflammatory factors such as TNF-α and IL-6, providing effective anti-inflammatory regulation.
Q
What benefits does it offer for sports nutrition and muscle recovery?
A
L-O-Phospho-Threonine improves muscle cell glycolysis efficiency to prolong exercise endurance, reduces creatine kinase levels post-exercise to relieve delayed muscle soreness, and accelerates lactate dehydrogenase reactions to shorten post-exercise recovery time.
Q
What makes L-O-Phospho-Threonine more stable than regular threonine?
A
The phosphorylation modification enhances the molecular polarity of threonine, which improves its water solubility and thermal stability. This broadens its suitability for various formulation development scenarios, including oral preparations and functional foods.
Q
What are the neuroprotective effects of L-O-Phospho-Threonine?
A
It upregulates glutathione peroxidase activity to scavenge free radicals and provides an antioxidant barrier. It also promotes the synthesis of brain-derived neurotrophic factor (BDNF) to maintain neuronal network stability and synaptic plasticity.
Q
In which product types is L-O-Phospho-Threonine commonly used?
A
It is widely used in sports nutrition supplements, postoperative recovery formulas, and anti-aging health products. Its phosphorylated structure also makes it suitable for oral preparations and functional food development, with clinical potential in assisting metabolic syndrome and neurodegenerative disease management.