Hot Products
0102030405
O-Phospho-L-serine Suppliers in China | Quality Dexfosfoserine from Trusted Factory
C3H8NO6P
ⓘ
Description
L-O-phosphoserine (O-Phospho-L-serine, CAS No. 407-41-0) is a phosphorylated derivative of serine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care. The following is a detailed introduction:
⚙
Technical Advantage Analysis
🧠
Neural Signal Regulation
As an agonist of the third group of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), it antagonizes mGluR1 and mGluR2 at the same time, accurately regulates neurotransmitter transmission and neuronal excitability, and improves cognitive function.
⚡
Metabolic Enhancement
Promotes phosphatidylserine synthesis and maintains cell membrane integrity; accelerates amino acid metabolism, supports protein synthesis, and optimizes energy utilization.
🔬
Stability Improvement
Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
✨
Core Role of Nutrition and Health Care
1
Neuroprotection and Cognitive Enhancement
●
Antioxidant Barrier: Upregulates glutathione peroxidase activity, scavenges free radicals, and reduces neuronal damage.
●
Synaptic Plasticity: Promotes the synthesis of brain-derived neurotrophic factor (BDNF) and enhances learning and memory abilities.
●
Emotional Regulation: Participates in the synthesis of serotonin and relieves anxiety and depression.
2
Immune Empowerment
●
Lymphocyte Activation: Enhances T/B cell receptor signal transduction, increases antibody secretion and diversity.
●
Anti-inflammatory Regulation: Inhibits the NF-κB pathway, reduces the secretion of pro-inflammatory factors TNF-α and IL-6, and relieves chronic inflammation.
3
Sleep Optimization
●
Circadian Rhythm Regulation: Promotes melatonin secretion, improves sleep difficulties and night awakening problems.
●
Improved Sleep Quality: Extends the deep sleep stage and enhances sleep recovery effects.
4
Cardiovascular Support
●
Blood Pressure Regulation: Assists in controlling the conduction of cardiac and vascular nerve impulses and stabilizes blood pressure levels.
●
Endothelial Protection: Enhances vascular antioxidant capacity and prevents atherosclerosis.
5
Application Scenario Expansion
🌐
Widely used in anti-fatigue dietary supplements, cognitive enhancement formulas and cardiovascular health products. Clinical studies have shown that it has the potential to assist in improving Alzheimer's disease and Parkinson's disease. Its phosphorylated structure makes it suitable for the development of oral preparations and functional foods, making it a targeted nutritional solution for serine upgrade replacement.
❓
Frequently Asked Questions (FAQ)
Q
What is L-O-Phosphoserine (O-Phospho-L-serine) and what is its CAS number?
L-O-Phosphoserine (also known as O-Phospho-L-serine) is a phosphorylated derivative of the amino acid serine. Its CAS number is 407-41-0. The introduction of a phosphate group significantly enhances its biological activity, water solubility, and functional diversity compared to standard serine.
Q
How does L-O-Phosphoserine support cognitive function and brain health?
L-O-Phosphoserine acts as an agonist of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8) to regulate neurotransmitter transmission. It also promotes the synthesis of brain-derived neurotrophic factor (BDNF), upregulates glutathione peroxidase to reduce neuronal oxidative damage, and participates in serotonin synthesis to support emotional balance and cognitive enhancement.
Q
What role does L-O-Phosphoserine play in immune system support?
L-O-Phosphoserine enhances T/B lymphocyte receptor signal transduction to increase antibody secretion, and inhibits the NF-κB inflammatory pathway to reduce the release of pro-inflammatory cytokines such as TNF-α and IL-6. This dual action provides meaningful support for both adaptive immunity and the regulation of chronic inflammation.
Q
Can L-O-Phosphoserine help improve sleep quality?
Yes. L-O-Phosphoserine promotes melatonin secretion to help regulate circadian rhythms, making it beneficial for individuals experiencing difficulty falling asleep or frequent night awakening. It also extends the duration of deep sleep stages, thereby enhancing overall sleep recovery and restorative effects.
Q
What are the main cardiovascular benefits of L-O-Phosphoserine?
L-O-Phosphoserine supports cardiovascular health by assisting in the regulation of cardiac and vascular nerve impulse conduction to help stabilize blood pressure levels. Additionally, it enhances the antioxidant capacity of vascular endothelial cells, which may help prevent the development of atherosclerosis and related cardiovascular conditions.
Q
What types of products and formulations is L-O-Phosphoserine suitable for?
Thanks to its phosphorylated structure and improved water solubility and thermal stability, L-O-Phosphoserine is well-suited for a wide range of applications including anti-fatigue dietary supplements, cognitive enhancement formulas, sleep support products, cardiovascular health solutions, oral preparations, and functional foods. Clinical research also suggests potential in assisting with neurodegenerative conditions such as Alzheimer's and Parkinson's disease.