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O-Phospho-L-serine Suppliers in China - Quality Dexfosfoserine from Leading Factory
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Description
L-O-phosphoserine (O-Phospho-L-serine, CAS No. 407-41-0) is a phosphorylated derivative of serine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care. The following is a detailed introduction:
Technical Advantage Analysis
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Neural Signal Regulation As an agonist of the third group of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), it antagonizes mGluR1 and mGluR2 at the same time, accurately regulates neurotransmitter transmission and neuronal excitability, and improves cognitive function.
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Metabolic Enhancement Promotes phosphatidylserine synthesis and maintains cell membrane integrity; accelerates amino acid metabolism, supports protein synthesis, and optimizes energy utilization.
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Stability Improvement Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
Core Role of Nutrition and Health Care
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1. Neuroprotection and Cognitive Enhancement
- Antioxidant Barrier: Upregulates glutathione peroxidase activity, scavenges free radicals, and reduces neuronal damage.
- Synaptic Plasticity: Promotes the synthesis of brain-derived neurotrophic factor (BDNF) and enhances learning and memory abilities.
- Emotional Regulation: Participates in the synthesis of serotonin and relieves anxiety and depression.
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2. Immune Empowerment
- Lymphocyte Activation: Enhances T/B cell receptor signal transduction, increases antibody secretion and diversity.
- Anti-inflammatory Regulation: Inhibits the NF-κB pathway, reduces the secretion of pro-inflammatory factors TNF-α and IL-6, and relieves chronic inflammation.
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3. Sleep Optimization
- Circadian Rhythm Regulation: Promotes melatonin secretion, improves sleep difficulties and night awakening problems.
- Improved Sleep Quality: Extends the deep sleep stage and enhances sleep recovery effects.
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4. Cardiovascular Support
- Blood Pressure Regulation: Assists in controlling the conduction of cardiac and vascular nerve impulses and stabilizes blood pressure levels.
- Endothelial Protection: Enhances vascular antioxidant capacity and prevents atherosclerosis.
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5. Application Scenario Expansion
Widely used in anti-fatigue dietary supplements, cognitive enhancement formulas and cardiovascular health products. Clinical studies have shown that it has the potential to assist in improving Alzheimer's disease and Parkinson's disease. Its phosphorylated structure makes it suitable for the development of oral preparations and functional foods, making it a targeted nutritional solution for serine upgrade replacement.
Frequently Asked Questions (FAQ)
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What is L-O-Phosphoserine (O-Phospho-L-serine)?
L-O-Phosphoserine (CAS No. 407-41-0) is a phosphorylated derivative of the amino acid serine. The addition of a phosphate group significantly enhances its biological activity and functional diversity, making it a valuable ingredient in nutrition and health care applications.
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How does L-O-Phosphoserine support brain and cognitive health?
It acts as an agonist of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), regulates neurotransmitter transmission, promotes BDNF synthesis for synaptic plasticity, and participates in serotonin production to help relieve anxiety and depression — all of which contribute to improved learning, memory, and overall cognitive function.
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What are the immune benefits of L-O-Phosphoserine?
L-O-Phosphoserine enhances T/B cell receptor signal transduction to boost antibody production and diversity. It also inhibits the NF-κB inflammatory pathway, reducing the secretion of pro-inflammatory cytokines such as TNF-α and IL-6, thereby alleviating chronic inflammation.
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Can L-O-Phosphoserine help improve sleep quality?
Yes. L-O-Phosphoserine promotes melatonin secretion to regulate circadian rhythms, which helps address sleep difficulties and night awakening. It has also been shown to extend the deep sleep stage, enhancing overall sleep recovery and quality.
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What cardiovascular benefits does L-O-Phosphoserine offer?
It assists in controlling cardiac and vascular nerve impulse conduction to help stabilize blood pressure levels. Additionally, it enhances vascular antioxidant capacity, providing endothelial protection and helping to prevent atherosclerosis.
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What types of products is L-O-Phosphoserine suitable for?
Due to its phosphorylated structure and improved water solubility and thermal stability, L-O-Phosphoserine is suitable for a wide range of applications including anti-fatigue dietary supplements, cognitive enhancement formulas, cardiovascular health products, oral preparations, and functional foods. It also shows clinical potential in supporting the management of Alzheimer's disease and Parkinson's disease.