Amino acids
0102030405
O-Phospho-L-serine / Dexfosfoserine/ L-O-phosphoserine/ L-O-phosphoserinate/
C3H8NO6P
Description
L-O-phosphoserine (O-Phospho-L-serine, CAS No. 407-41-0) is a phosphorylated derivative of serine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care. The following is a detailed introduction:
Technical Advantage Analysis
Neural Signal Regulation: As an agonist of the third group of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), it antagonizes mGluR1 and mGluR2 at the same time, accurately regulates neurotransmitter transmission and neuronal excitability, and improves cognitive function.
Metabolic Enhancement: Promotes phosphatidylserine synthesis and maintains cell membrane integrity; accelerates amino acid metabolism, supports protein synthesis, and optimizes energy utilization.
Stability Improvement: Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
Core Role of Nutrition and Health Care
1.Neuroprotection and Cognitive Enhancement
Antioxidant Barrier: Upregulates glutathione peroxidase activity, scavenges free radicals, and reduces neuronal damage.
Synaptic plasticity: Promotes the synthesis of brain-derived neurotrophic factor (BDNF) and enhances learning and memory abilities.
Emotional regulation: Participates in the synthesis of serotonin and relieves anxiety and depression.
2.Immune empowerment
Lymphocyte activation: Enhances T/B cell receptor signal transduction, increases antibody secretion and diversity.
Anti-inflammatory regulation: Inhibits the NF-κB pathway, reduces the secretion of pro-inflammatory factors TNF-α and IL-6, and relieves chronic inflammation.
3.Sleep optimization
Circadian rhythm regulation: Promotes melatonin secretion, improves sleep difficulties and night awakening problems.
Improved sleep quality: Extends the deep sleep stage and enhances sleep recovery effects.
4.Cardiovascular support
Blood pressure regulation: Assists in controlling the conduction of cardiac and vascular nerve impulses and stabilizes blood pressure levels.
Endothelial protection: Enhances vascular antioxidant capacity and prevents atherosclerosis.
5.Application scenario expansion
Widely used in anti-fatigue dietary supplements, cognitive enhancement formulas and cardiovascular health products. Clinical studies have shown that it has the potential to assist in improving Alzheimer's disease and Parkinson's disease. Its phosphorylated structure makes it suitable for the development of oral preparations and functional foods, making it a targeted nutritional solution for serine upgrade replacement.