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L-O-Phospho-L-Serine Suppliers and Factory in China - Quality Dexfosfoserine Products Available
C3H8NO6P
Description
L-O-phosphoserine (O-Phospho-L-serine, CAS No. 407-41-0) is a phosphorylated derivative of serine. By introducing a phosphate group, its biological activity and functional diversity are significantly enhanced, showing unique value in the field of nutrition and health care. The following is a detailed introduction:
Technical Advantage Analysis
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Neural Signal Regulation
As an agonist of the third group of metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), it antagonizes mGluR1 and mGluR2 at the same time, accurately regulates neurotransmitter transmission and neuronal excitability, and improves cognitive function.
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Metabolic Enhancement
Promotes phosphatidylserine synthesis and maintains cell membrane integrity; accelerates amino acid metabolism, supports protein synthesis, and optimizes energy utilization.
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Stability Improvement
Phosphorylation modification enhances molecular polarity, improves water solubility and thermal stability, and broadens the application scenarios of formulation development.
Core Role of Nutrition and Health Care
1
Neuroprotection and Cognitive Enhancement
Antioxidant Barrier: Upregulates glutathione peroxidase activity, scavenges free radicals, and reduces neuronal damage.
Synaptic Plasticity: Promotes the synthesis of brain-derived neurotrophic factor (BDNF) and enhances learning and memory abilities.
Emotional Regulation: Participates in the synthesis of serotonin and relieves anxiety and depression.
2
Immune Empowerment
Lymphocyte Activation: Enhances T/B cell receptor signal transduction, increases antibody secretion and diversity.
Anti-inflammatory Regulation: Inhibits the NF-κB pathway, reduces the secretion of pro-inflammatory factors TNF-α and IL-6, and relieves chronic inflammation.
3
Sleep Optimization
Circadian Rhythm Regulation: Promotes melatonin secretion, improves sleep difficulties and night awakening problems.
Improved Sleep Quality: Extends the deep sleep stage and enhances sleep recovery effects.
4
Cardiovascular Support
Blood Pressure Regulation: Assists in controlling the conduction of cardiac and vascular nerve impulses and stabilizes blood pressure levels.
Endothelial Protection: Enhances vascular antioxidant capacity and prevents atherosclerosis.
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Application Scenario Expansion
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Broad Application Potential
Widely used in anti-fatigue dietary supplements, cognitive enhancement formulas and cardiovascular health products. Clinical studies have shown that it has the potential to assist in improving Alzheimer's disease and Parkinson's disease. Its phosphorylated structure makes it suitable for the development of oral preparations and functional foods, making it a targeted nutritional solution for serine upgrade replacement.
Frequently Asked Questions (FAQ)
Q
What is L-O-Phosphoserine (O-Phospho-L-serine) and what is its CAS number?
A
L-O-Phosphoserine (O-Phospho-L-serine) is a phosphorylated derivative of the amino acid serine, with the molecular formula C₃H₈NO₆P and CAS No. 407-41-0. The introduction of a phosphate group significantly enhances its biological activity and functional diversity compared to standard serine.
Q
How does L-O-Phosphoserine support brain health and cognitive function?
A
L-O-Phosphoserine acts as an agonist of Group III metabotropic glutamate receptors (mGluR4, mGluR6, mGluR7, mGluR8), regulating neurotransmitter transmission and neuronal excitability. It also promotes BDNF synthesis to enhance learning and memory, upregulates glutathione peroxidase to protect neurons, and participates in serotonin synthesis to support emotional balance.
Q
What are the immune benefits of O-Phospho-L-serine?
A
O-Phospho-L-serine enhances immune function by boosting T/B cell receptor signal transduction and increasing antibody secretion. It also exerts anti-inflammatory effects by inhibiting the NF-κB pathway and reducing the secretion of pro-inflammatory cytokines TNF-α and IL-6, helping to relieve chronic inflammation.
Q
Can L-O-Phosphoserine help improve sleep quality?
A
Yes. L-O-Phosphoserine promotes melatonin secretion to regulate circadian rhythms, helping address sleep difficulties and night awakening. It has also been shown to extend the deep sleep stage, improving overall sleep recovery and quality.
Q
What cardiovascular benefits does O-Phospho-L-serine offer?
A
O-Phospho-L-serine supports cardiovascular health by assisting in the control of cardiac and vascular nerve impulse conduction to help stabilize blood pressure. It also enhances the antioxidant capacity of vascular endothelial cells, providing protection against atherosclerosis development.
Q
What types of products is L-O-Phosphoserine suitable for formulation?
A
Thanks to its improved water solubility and thermal stability from phosphorylation modification, L-O-Phosphoserine is well-suited for use in anti-fatigue dietary supplements, cognitive enhancement formulas, cardiovascular health products, oral preparations, and functional foods. It also shows clinical potential as an adjunct ingredient in products targeting Alzheimer's disease and Parkinson's disease management.