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China Suppliers Factory for Riboflavin Sodium Phosphate (Riboflavin-5’-Phosphate) - Vitamin B2 R5P Crystalline Powder
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China Suppliers Factory for Riboflavin Sodium Phosphate (Riboflavin-5’-Phosphate) - Vitamin B2 R5P Crystalline Powder

Riboflavin 5'-phosphate is a vibrant yellow to orange crystalline powder that exhibits excellent solubility in water, while being only slightly soluble in ethanol. As a leading supplier and factory for riboflavin 5'-phosphate in China, we ensure high-quality products that meet industry standards. Our commitment to providing premium-grade riboflavin 5'-phosphate makes us a trusted choice for manufacturers and businesses seeking reliable ingredients
  • CAS: 6184-17-4

C17H24N4NaO11P
Riboflavin Sodium Phosphate Structure

Description
Riboflavin Sodium Phosphate (R5P) is an active phosphate derivative of vitamin B2 (riboflavin). It significantly improves water solubility and bioavailability through modification of phosphate groups. Its technical advantages and nutritional and health value far exceed ordinary riboflavin.

Comparison of Technical Advantages
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Absorption and Utilization Rate Increased The solubility of riboflavin sodium phosphate in water reaches 50mg/mL, which is dozens of times that of ordinary riboflavin. It can be made into multiple dosage forms such as injection and eye drops, breaking through the limitation that riboflavin can only be absorbed orally, and the clinical application scenarios are significantly expanded.
Enhanced Metabolic Activity As a precursor of coenzymes FAD and FMN, it directly participates in the energy metabolism of the cell respiratory chain, promotes the conversion efficiency of sugar, fat and protein, and its biological activity is about 40% higher than that of riboflavin.
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Stability Upgrade It is thermally stable under acidic to neutral conditions, and its light-resistant decomposition ability is enhanced, which is convenient for processing, storage and multi-scenario application.

In-Depth Analysis of Nutrition and Health
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Energy Metabolism Engine: Activate mitochondrial oxidative phosphorylation reaction, improve ATP synthesis efficiency, and improve exercise endurance and fatigue recovery.
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Antioxidant Defense System: Remove free radicals, inhibit lipid peroxidation, protect cell membrane integrity, delay aging and chronic disease risks.
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Mucosal Health Protection: Repair oral and gastrointestinal mucosa, prevent angular cheilitis, cheilitis, glossitis, and relieve mucosal damage after radiotherapy and chemotherapy.
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Visual Function Support: Maintain retinal photoreceptor cell metabolism, reduce blue light damage, improve night vision and visual fatigue.
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Blood System Strengthening: Promote iron absorption and utilization, increase hemoglobin synthesis, and assist in improving iron deficiency anemia.

Clinical and Health Care Applications
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Medical Field Treatment of vitamin B2 deficiency with expanded clinical dosage forms including injections and eye drops.
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Food Industry Nutritional enhancer in dairy products and grains, improving overall nutritional profile.
Cosmetics Field Improves skin barrier function and supports skin health at the cellular level.
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Animal Feed Improves the growth performance of livestock and poultry by adding to feed formulations.
Its multi-target mechanism of action (metabolic regulation + antioxidant + tissue repair) provides an integrated solution for health intervention and becomes the preferred choice for upgrading and replacing vitamin B2.

Frequently Asked Questions (FAQ)
What is Riboflavin Sodium Phosphate (R5P)?
Riboflavin Sodium Phosphate (R5P) is an active phosphate derivative of vitamin B2 (riboflavin). It is chemically modified with phosphate groups to significantly enhance water solubility (up to 50mg/mL) and bioavailability, making it far more versatile and effective than standard riboflavin.
How does Riboflavin Sodium Phosphate differ from regular riboflavin?
Compared to regular riboflavin, Riboflavin Sodium Phosphate offers dramatically higher water solubility (dozens of times greater), approximately 40% higher biological activity, enhanced thermal and light stability, and the ability to be formulated into injectable and topical dosage forms — not just oral supplements.
What are the main health benefits of Riboflavin Sodium Phosphate?
Key health benefits include boosting energy metabolism via ATP synthesis, providing antioxidant protection against free radicals, repairing oral and gastrointestinal mucosa, supporting retinal health and visual function, and promoting iron absorption to assist with iron deficiency anemia.
In which industries is Riboflavin Sodium Phosphate commonly used?
Riboflavin Sodium Phosphate is widely applied across multiple sectors: the medical field (B2 deficiency treatment, injections, eye drops), the food industry (nutritional fortification of dairy and grains), the cosmetics industry (skin barrier enhancement), and animal agriculture (feed additive for livestock and poultry growth performance).
Is Riboflavin Sodium Phosphate stable during processing and storage?
Yes. Riboflavin Sodium Phosphate demonstrates improved thermal stability under acidic to neutral pH conditions and enhanced resistance to light-induced decomposition compared to regular riboflavin. This makes it highly suitable for a wide range of manufacturing processes and storage environments.
Why is Riboflavin Sodium Phosphate considered a preferred upgrade over standard vitamin B2?
Its multi-target mechanism — combining metabolic regulation, antioxidant defense, and tissue repair — along with superior solubility, bioavailability, and formulation flexibility, makes it a comprehensive and effective replacement for standard vitamin B2 across clinical, nutritional, and industrial applications.