Bisbentiamine - Vitamin B1 Derivative from China Suppliers and Factory | CAS 2667-89-2
Bisbentiamine (CAS No. 2667-89-2) is a derivative of vitamin B1 (thiamine), with the chemical name of dibenzoyl disulfide thiamine, the molecular formula of C₃₈H₄₂N₈O₆S₂, and a molecular weight of 770.92. Its structural feature is that two benzoyl groups are connected by a disulfide bond, which gives it unique fat solubility and stability.
As a derivative of vitamin B1, bisbenzylthiamine has multiple potentials in the field of nutritional supplementation by optimizing bioavailability:
Compared with water-soluble thiamine, its fat-soluble structure is easier to pass through the cell membrane, improving absorption efficiency, thereby increasing the level of active coenzymes such as thiamine pyrophosphate (TPP) in the body, supporting energy metabolism and nervous system function.
By activating transketolase, it promotes the normalization of glucose metabolism and reduces the accumulation of advanced glycation end products (AGEs), thereby combating oxidative damage and diabetic complications (such as neuropathy and retinopathy) caused by hyperglycemia.
Some dietary supplements combine it with other B vitamins (such as thiamine sulfozincate) to optimize metabolic pathways and enhance anti-fatigue and neuroprotective effects through the synergistic effect of coenzyme forms.
The application of bisbenzamide in dietary supplements is mainly concentrated in the following directions:
For people with high blood sugar, it protects blood vessels and nerve tissues by inhibiting the formation of AGEs, and is often used to prevent complications such as diabetic neuropathy.
As a coenzyme, it participates in the tricarboxylic acid cycle and promotes the conversion of carbohydrates into energy. It is suitable for people with high physical exertion or easy fatigue.
Improve vitamin B1 deficiency caused by alcoholism or malnutrition, and maintain nerve conduction function.