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Bisbentiamine Suppliers in China - High-Quality Thiamine Disulfide from Trusted Factory
Basic Information and Chemical Properties
Bisbentiamine (CAS No. 2667-89-2) is a derivative of vitamin B1 (thiamine), with the chemical name of dibenzoyl disulfide thiamine, the molecular formula of C₃₈H₄₂N₈O₆S₂, and a molecular weight of 770.92. Its structural feature is that two benzoyl groups are connected by a disulfide bond, which gives it unique fat solubility and stability.
CAS No.
2667-89-2
Molecular Formula
C₃₈H₄₂N₈O₆S₂
Molecular Weight
770.92
Density
1.331 g/cm³
Melting Point
140 – 145 °C
Boiling Point
987.4 °C (predicted)
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Storage requirement: Keep away from light and moisture at room temperature to maintain stability and potency.
Functional Mechanism and Nutritional Health Effects
As a derivative of vitamin B1, bisbenzylthiamine has multiple potentials in the field of nutritional supplementation by optimizing bioavailability:
1
Enhanced Bioavailability
Compared with water-soluble thiamine, its fat-soluble structure is easier to pass through the cell membrane, improving absorption efficiency, thereby increasing the level of active coenzymes such as thiamine pyrophosphate (TPP) in the body, supporting energy metabolism and nervous system function.
2
Regulating Sugar Metabolism and Anti-Oxidation
By activating transketolase, it promotes the normalization of glucose metabolism and reduces the accumulation of advanced glycation end products (AGEs), thereby combating oxidative damage and diabetic complications (such as neuropathy and retinopathy) caused by hyperglycemia.
3
Synergistic Effect
Some dietary supplements combine it with other B vitamins (such as thiamine sulfozincate) to optimize metabolic pathways and enhance anti-fatigue and neuroprotective effects through the synergistic effect of coenzyme forms.
Application Scenarios and Product Examples
The application of bisbenzamide in dietary supplements is mainly concentrated in the following directions:
1
Diabetes and Metabolic Health
For people with high blood sugar, it protects blood vessels and nerve tissues by inhibiting the formation of AGEs, and is often used to prevent complications such as diabetic neuropathy.
2
Energy Metabolism and Anti-Fatigue
As a coenzyme, it participates in the tricarboxylic acid cycle and promotes the conversion of carbohydrates into energy. It is suitable for people with high physical exertion or easy fatigue.
3
Nervous System Support
Improve vitamin B1 deficiency caused by alcoholism or malnutrition, and maintain nerve conduction function.
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Dieselamide has become a popular ingredient in the field of nutritional supplements due to its high bioavailability and multiple metabolic regulation functions. However, its application still needs to be combined with individual needs and scientifically supplemented on the basis of a balanced diet. In the future, with the advancement of synthetic biology technology and the deepening of clinical research, the potential of this ingredient in the field of chronic disease prevention and precision nutrition will be further released.
Frequently Asked Questions (FAQ)
Q
What is Bisbentiamine and how does it differ from regular Vitamin B1?
Bisbentiamine (CAS No. 2667-89-2) is a fat-soluble derivative of vitamin B1 (thiamine). Unlike water-soluble thiamine, its disulfide-bonded benzoyl structure allows it to more easily pass through cell membranes, resulting in significantly improved absorption and bioavailability compared to standard Vitamin B1 supplements.
Q
How does Bisbentiamine help with diabetes and blood sugar management?
Bisbentiamine activates transketolase, an enzyme that helps normalize glucose metabolism. It also reduces the accumulation of advanced glycation end products (AGEs), which are harmful compounds formed during high blood sugar conditions. This dual action helps protect blood vessels and nerve tissues, lowering the risk of diabetic complications such as neuropathy and retinopathy.
Q
Who can benefit most from taking Bisbentiamine supplements?
Bisbentiamine is particularly beneficial for individuals with high blood sugar or diabetes, people experiencing physical fatigue or high energy demands, those with Vitamin B1 deficiency due to alcoholism or malnutrition, and individuals seeking neuroprotective or anti-fatigue support through nutritional supplementation.
Q
What are the key physical and chemical properties of Bisbentiamine?
Bisbentiamine has a molecular formula of C₃₈H₄₂N₈O₆S₂ and a molecular weight of 770.92. Its density is 1.331 g/cm³, melting point is 140–145°C, and its predicted boiling point is 987.4°C. It should be stored away from light and moisture at room temperature to ensure stability.
Q
Can Bisbentiamine be combined with other B vitamins in supplements?
Yes. Bisbentiamine is often formulated alongside other B vitamins, such as thiamine sulfozincate, to create synergistic effects. These combinations help optimize metabolic pathways, enhance anti-fatigue benefits, and provide stronger neuroprotective effects through the complementary actions of different coenzyme forms.
Q
Is Bisbentiamine safe to use, and are there any considerations before taking it?
Bisbentiamine is generally considered safe as a nutritional supplement ingredient. However, its use should be tailored to individual health needs and used as part of a balanced diet. It is advisable to consult a healthcare professional before starting supplementation, especially for individuals with pre-existing medical conditions or those taking prescription medications.