Bisbentiamine Suppliers and Factory in China | Thiamine Disulfide for Enhanced Health Benefits
Basic Information and Chemical Properties
| Chemical Name | Dibenzoyl disulfide thiamine |
|---|---|
| CAS Number | 2667-89-2 |
| Molecular Formula / Weight | C₃₈H₄₂N₈O₆S₂ / 770.92 |
| Density & Melting Point | Density: 1.331 g/cm³ | Melting Point: 140-145℃ |
| Boiling Point | 987.4℃ (predicted value) |
| Storage Conditions | Store away from light and moisture at room temperature. |
Functional Mechanism and Nutritional Health Effects
As a derivative of vitamin B1, bisbenzylthiamine has multiple potentials in the field of nutritional supplementation by optimizing bioavailability:
Enhanced Bioavailability
Compared with water-soluble thiamine, its fat-soluble structure is easier to pass through the cell membrane, improving absorption efficiency, thereby increasing the level of active coenzymes such as thiamine pyrophosphate (TPP) in the body, supporting energy metabolism and nervous system function.
Regulating Sugar Metabolism & Anti-Oxidation
By activating transketolase, it promotes the normalization of glucose metabolism and reduces the accumulation of advanced glycation end products (AGEs), thereby combating oxidative damage and diabetic complications (such as neuropathy and retinopathy) caused by hyperglycemia.
Synergistic Effect
Some dietary supplements combine it with other B vitamins (such as thiamine sulfozincate) to optimize metabolic pathways and enhance anti-fatigue and neuroprotective effects through the synergistic effect of coenzyme forms.
Application Scenarios and Product Examples
The application of bisbenzamide in dietary supplements is mainly concentrated in the following directions:
Diabetes and Metabolic Health
For people with high blood sugar, it protects blood vessels and nerve tissues by inhibiting the formation of AGEs, and is often used to prevent complications such as diabetic neuropathy.
Energy Metabolism and Anti-Fatigue
As a coenzyme, it participates in the tricarboxylic acid cycle and promotes the conversion of carbohydrates into energy. It is suitable for people with high physical exertion or easy fatigue.
Nervous System Support
Improve vitamin B1 deficiency caused by alcoholism or malnutrition, and maintain nerve conduction function.
Frequently Asked Questions (FAQ)
What is Bisbentiamine?
Bisbentiamine (CAS No. 2667-89-2) is a fat-soluble derivative of Vitamin B1 (thiamine) designed for higher bioavailability, cellular absorption, and enhanced metabolic stability.
Why is Bisbentiamine more bioavailable than standard Vitamin B1?
Unlike water-soluble thiamine, the fat-soluble structure formed by its disulfide bond allows Bisbentiamine to pass through cell membranes more easily, resulting in higher levels of active coenzymes like TPP.
How does Bisbentiamine help with diabetic complications?
It activates transketolase to normalize glucose metabolism and inhibits the accumulation of advanced glycation end products (AGEs), protecting nerve and vascular tissues from oxidative damage.
What are the main applications of Bisbentiamine in supplements?
It is primarily formulated for diabetic nerve health, energy and anti-fatigue metabolism support, and nervous system repair associated with vitamin B1 deficiency.
How should Bisbentiamine raw material be stored?
It should be stored at room temperature, strictly sealed and protected away from light, heat, and moisture to maintain its chemical stability.
Can Bisbentiamine be combined with other B-complex vitamins?
Yes, it often works synergistically with other B-group vitamins to optimize metabolic pathways and enhance neuroprotective and anti-fatigue performance.