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Bisbentiamine - Premium Thiamine Disulfide Supplier and Factory in China - High Purity Vitamin B1 Derivative
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Bisbentiamine - Premium Thiamine Disulfide Supplier and Factory in China - High Purity Vitamin B1 Derivative

Bisbentiamine (CAS No. 2667-89-2) is a powerful vitamin B1 (thiamine) derivative, also known as dibenzoyl disulfide thiamine. With a molecular formula of C₃₈H₄₂N₈O₆S₂ and a molecular weight of 770.92, this compound is crucial in enhancing overall health. As a leading supplier and factory based in China, we are dedicated to providing high-quality Bisbentiamine to meet your needs. Trust our expertise as a top-tier supplier in the industry to deliver reliable and effective vitamin derivatives. Experience the benefits of Bisbentiamine today with our premium products sourced directly from our state-of-the-art factory in China.

    Basic Information and Chemical Properties

    Bisbentiamine (CAS No. 2667-89-2) is a derivative of vitamin B1 (thiamine), with the chemical name of dibenzoyl disulfide thiamine, the molecular formula of C₃₈H₄₂N₈O₆S₂, and a molecular weight of 770.92. Its structural feature is that two benzoyl groups are connected by a disulfide bond, which gives it unique fat solubility and stability.

    CAS Number
    2667-89-2
    Molecular Formula
    C₃₈H₄₂N₈O₆S₂
    Molecular Weight
    770.92
    Density
    1.331 g/cm³
    Melting Point
    140 - 145 ℃
    Boiling Point (Predicted)
    987.4 ℃

    Storage Condition: It needs to be stored away from light and moisture at room temperature.

    Functional Mechanism and Nutritional Health Effects

    As a derivative of vitamin B1, bisbenzylthiamine has multiple potentials in the field of nutritional supplementation by optimizing bioavailability:

    1. Enhanced Bioavailability

    Compared with water-soluble thiamine, its fat-soluble structure is easier to pass through the cell membrane, improving absorption efficiency, thereby increasing the level of active coenzymes such as thiamine pyrophosphate (TPP) in the body, supporting energy metabolism and nervous system function.

    2. Regulating Sugar Metabolism & Anti-Oxidation

    By activating transketolase, it promotes the normalization of glucose metabolism and reduces the accumulation of advanced glycation end products (AGEs), thereby combating oxidative damage and diabetic complications (such as neuropathy and retinopathy) caused by hyperglycemia.

    3. Synergistic Effect

    Some dietary supplements combine it with other B vitamins (such as thiamine sulfozincate) to optimize metabolic pathways and enhance anti-fatigue and neuroprotective effects through the synergistic effect of coenzyme forms.

    Application Scenarios and Product Examples

    The application of bisbenzamide in dietary supplements is mainly concentrated in the following directions:

    1. Diabetes and Metabolic Health

    For people with high blood sugar, it protects blood vessels and nerve tissues by inhibiting the formation of AGEs, and is often used to prevent complications such as diabetic neuropathy.

    2. Energy Metabolism and Anti-Fatigue

    As a coenzyme, it participates in the tricarboxylic acid cycle and promotes the conversion of carbohydrates into energy. It is suitable for people with high physical exertion or easy fatigue.

    3. Nervous System Support

    Improve vitamin B1 deficiency caused by alcoholism or malnutrition, and maintain nerve conduction function.

    Dieselamide has become a popular ingredient in the field of nutritional supplements due to its high bioavailability and multiple metabolic regulation functions. However, its application still needs to be combined with individual needs and scientifically supplemented on the basis of a balanced diet. In the future, with the advancement of synthetic biology technology and the deepening of clinical research, the potential of this ingredient in the field of chronic disease prevention and precision nutrition will be further released.

    Frequently Asked Questions (FAQ)

    1. What is Bisbentiamine?
    Bisbentiamine (CAS No. 2667-89-2) is a specialized derivative of vitamin B1 (thiamine), chemically known as dibenzoyl disulfide thiamine. It features two benzoyl groups linked by a disulfide bond, providing enhanced stability and fat solubility.
    2. How does Bisbentiamine differ from standard Vitamin B1?
    Unlike standard water-soluble thiamine, Bisbentiamine has a fat-soluble structure that penetrates cell membranes more efficiently. This results in significantly higher bioavailability and faster elevation of active coenzymes like thiamine pyrophosphate (TPP) in the body.
    3. How does it help manage diabetic complications?
    Bisbentiamine activates the enzyme transketolase, which normalizes glucose metabolism pathways and inhibits the buildup of advanced glycation end products (AGEs). This action protects vascular and nerve tissues from oxidative stress, helping alleviate diabetic neuropathy and retinopathy.
    4. Why is Bisbentiamine effective against fatigue?
    As a coenzyme precursor, it directly supports the tricarboxylic acid (TCA) cycle, accelerating the conversion of carbohydrates into usable cellular energy (ATP), which makes it suitable for combating physical exhaustion and high energy consumption.
    5. Can Bisbentiamine be combined with other nutrients?
    Yes. In dietary formulations, it is frequently paired with other B vitamins (such as thiamine sulfozincate) to produce synergistic effects across metabolic pathways, providing stronger neuroprotective and anti-fatigue benefits.
    6. What are the proper storage conditions for Bisbentiamine?
    To maintain its chemical stability and physical properties, Bisbentiamine should be stored at room temperature, sealed away from direct light and moisture.